Brain Health

As spermidine research expands, an ingredient commercialized nearly 90 years ago is getting a second look from manufacturers seeking whole-food sources of the compound alongside protein and fiber.

A new analysis of 5 randomized controlled trials finds a split picture: some evidence of benefit when creatine is added to standard treatment, and 3 trials that found no effect.

Maypro's new distribution partnership with Asahi Group Foods brings a clinically studied milk peptide to North American formulators targeting the cognitive health category.

Nutrition directly impacts cognitive health, which means that dietary recommendations have the potential to support cognitive health outcomes. This Op-Ed explores the existing research that connects diets and specific nutrients with cognitive health, and what we still need to learn to develop comprehensive recommendations that support long-term cognitive health outcomes.

From energy and focus to long-term neuroprotection, the brain health category is rich with opportunities for unique and effective formulations.

The formulation blends micronized creatine, HMB, and pomegranate polyphenols for age-related muscle decline and support for cognition.

Emerging science presented at a major NAD+ metabolism conference is shifting attention from simply raising NAD+ levels toward preserving them, and botanical approaches targeting the CD38 enzyme are at the center of that discussion.

As creatine innovation evolves beyond traditional gym performance, manufacturers are developing clinically supported formats aimed at brain energy metabolism, cellular resilience, healthy aging, and GLP-1-associated muscle preservation.

Organic matcha is combined with the company’s proprietary AlphaWave L-Theanine, reflecting consumer interest in energy without caffeine.

Explore the latest science on eye health supplements, the shift to lifelong foundational support, and how eye health and cognition support overlap.

From infant formula to healthy aging, eye health products are taking on a new dimension with benefit stacking and formulation into more complex matrices.

A new PLT Health Solutions-Alethios collaboration focused on decentralized clinical research reflects growing demand among nutraceutical manufacturers for product-specific evidence.

The new lion’s mane mycelium ingredient from Nammex enters the cognitive health category with a focus on analytical verification and standardized erinacine A content.

Kyowa Hakko to debut research on Cognizin Citicoline at ISSN 2026, revealing how a single 500 mg dose impacts acute cognitive performance and brain waves.

Recent molecular research finds an inter-organ communication pathway facilitated by aged garlic extract, revealing a potential mechanism for addressing age-related muscle decline.

The acquisition strengthens the gummy supplement manufacturer North American production capabilities and positions the company for continued growth in functional delivery formats.

Once a lesser-known category, postbiotics are quickly emerging as targeted, science-backed ingredients with applications spanning immunity, beauty-from-within, and stress support, reshaping the future of biotics innovation.

The ingredient supplier is advancing a broader longevity platform centered on pairing mechanistic aging science with clinically measurable benefits in mobility, cognition, and performance.

Nutritional Outlook offers a practical guide for industry professionals on multivitamin efficacy, formulation trends, and regulatory considerations.

Herbalist & Alchemist introduces a blended mycelium and fruiting body lion’s mane formula, reflecting rising demand for clinically relevant, clean-label nootropics.

A randomized controlled trial shows Zensera delivers same-day cognitive benefits and supports emotional balance under stress.

Latest research on magnesium L-threonate highlights cognitive, sleep, and stress benefits as demand for clinically backed brain health ingredients grows.

The study highlights how the ingredient from Aker BioMarine is able to bypass the blood-brain barrier to deliver omega-3 fatty acids.

In a chat with Nutritional Outlook, biomedicine professor Mathias Ziegler explores the complexities of NAD+ metabolism, highlighting emerging research on CD38, mitochondrial dynamics, and the gap between biomarker gains and real-world outcomes.

As research expands and new consumer segments emerge, creatine is evolving beyond performance nutrition into cognitive health, healthy aging, and daily wellness applications, bringing new opportunities and challenges for formulators.