Stress & Sleep

In a chat with Nutritional Outlook, biomedicine professor Mathias Ziegler explores the complexities of NAD+ metabolism, highlighting emerging research on CD38, mitochondrial dynamics, and the gap between biomarker gains and real-world outcomes.

A new randomized, placebo-controlled trial suggests that a black seed–derived ingredient may support cortisol balance, endocrine function, and multi-system stress adaptation in moderately stressed adults.

From stress and cognitive support to formulation challenges and regulatory considerations, this FAQ explores the science and market forces shaping ashwagandha’s role in modern nutraceuticals.

The randomized placebo-controlled trial showed Samriddh’s Bacopa monnieri extract significantly improved perceived stress, sleep quality, and cortisol levels in adults with non-chronic stress.

While adaptogens do not have an official scientific classification, they offer a compelling solution to chronic stress, informed by traditional Eastern practices, but approached through a more modern Western lens.

ThymoQuin Cortisol Support, containing a standardized black seed extract, has been clinically evaluated for effects on immune system and mood support.

Bonafide Health, LLC introduces Noctera, a melatonin-free supplement clinically studied to improve sleep quality and duration in perimenopausal and postmenopausal women.

The saffron extract recently received a license approval for stress-related health claims from the Ministry of Food and Drug Safety in South Korea, a growing market for this health category.

A growing number of innovative nutraceutical solutions are coming to market that help users deal with everyday stressors to improve sleep and quality of life.

A randomized, double-blind, placebo-controlled trial shows Magtein magnesium L-threonate from ThreoTech supports cognition, brain age, and sleep-related measures in adults.

A recent study explored the connection of TurmXTRA and Prolanza and if they can help with neurodegenerative disorders.

Supplementation with the formulated PEA ingredient resulted in improved heart rate variability, a marker of stress resilience.

Nutritional Outlook interviews ADM's Vaughn DuBow at SupplySide Global to discuss the company's recent Sleep, Stress, and Mood report.

The study from the American Heart Association (AHA) found that people with chronic insomnia who took melatonin long-term were found to be at higher risk of heart failure diagnosis, hospitalization, and death.

Nonpsychoactive cannabinoids like CBN, CBG, and CBDA support sleep, pain relief, and metabolism. Learn about their science, safety, and potential in functional foods and supplements.

Backed by clinical trials, the extended-release ashwagandha extract from Nutriventia, called Prolanza, supports stress relief, sleep, and cognitive health.

The latest trends and innovations in magnesium products.

At 125 mg, the bioavailability of extract Zenroot from OmniActive was compared to other ashwagandha extracts, as well as its effect on reducing stress and anxiety.

A 12-week clinical trial suggests that Affron from Pharmactive Biotech Products may help improve mood in adults experiencing mild depression symptoms.

A recent study explored Monteloeder’s RelaxPLX, a lemon verbena extract, and how it could be beneficial for teenagers with improving their sleep quality and relaxation.

Natural Remedies announced its latest innovation, an ashwagandha supplement which may help with stress support, energy, and endurance.

The presentation will explain the effects of Serezin on discomfort reduction and sleep support, highlighting results in a women-only cohort analysis.

Through recent research, Q-actin, a supplement produced from cucumber extract, may help improve sleep quality, finger dexterity, and cognitive wellness.

The low-dose plant-based ingredients, Sleeproot and Zenroot, are expected to grow the company’s presence in the expanding European nutraceutical market.

Nektium announced their new stress relief and sleep support supplement called Vanizem, which will be showcased at the upcoming Vitafoods Europe 2025.