Q-actin may provide healthy older adults with better sleep, dexterity, and cognitive wellness

IminoTech Inc., revealed in a recent press release, new research from a randomized and placebo-controlled study that was published in Frontiers in Nutrition.^1,2 The clinical research initiative investigated the effects of Q-actin, their patented cucumber extract (Cucumis sativus), which is standardized to >1%, on physical fitness and mental wellbeing. Data showed that Q-actin may help with sleep quality and finger dexterity in healthy older adults.¹

“Sleep disturbances are increasingly common with age and often managed with pharmaceuticals that can have undesirable side effects,” said Dr. Amanda Lloyd, lead author of the study.¹ “Our findings suggest that Q-actin offers a gentle, effective, and natural alternative by supporting the body’s own melatonin pathways.”

A previous study³ found that the Q-actin cucumber supplement could be beneficial to joint health such as, joint comfort and mobility. With this recent study¹, improvement in sleep quality and cognitive wellness can be added as potential benefits.

“We’re excited to see Q-actin demonstrate such broad potential across physical and mental wellness,” said Shil Kothari, CEO of IminoTech.¹ “A natural ingredient that supports joint, sleep, and cognitive health from a single low daily dose of just 20 milligrams opens exciting formulation opportunities for supplements and functional beverages.”

To gather research, the study utilized 47 healthy adults who were between the ages of 50 to 78 years old. Participants were then randomized and were either given placebo gummies or two Q-actin gummies. The study took place over the course of 12 weeks. According to the press release,¹ “Participants were not selected for sleep or cognitive complaints and were asked to maintain their usual diet and activity routines.” To analyze sleep quality, researchers utilized the Pittsburgh Sleep Quality Index (PSQI) and for neuromuscular function they used the Nine-Hole Peg Test. Researchers also collected urine samples from participants to assess primary metabolites and melatonin levels.¹

Results from the study found¹:

1. Melatonin, 6-sulfatoxymelatonin, and 6-hydroxymelatonin levels increased according to urine samples
2. Sleep quality improved
3. Finger dexterity increased
4. A compliance rate of more than 99% and no serious adverse events were reported

“The increase in melatonin and its metabolites may be mechanistically linked to Q-actin’s known anti-inflammatory effects, particularly its ability to modulate pro-inflammatory cytokines like tumor necrosis factor-alpha,” said Kothari.¹ “Q-actin’s remarkably low daily serving size and multifunctional benefits make it an ideal standalone or combination ingredient for products that support healthy aging.”

References

1. New Study Links Q-ActinTM to better sleep, Dexterity and Cognitive Wellness in healthy older adults https://www.iminotech.com/post/new-study-links-q-actin-to-better-sleep-dexterity-and-cognitive-wellness-in-healthy-older-adults (accessed May 23, 2025).
2. Lloyd, A. J.; Nash, R. J.; Warren-Walker, A.; Watson, A.; Martin, M. P. M.; Davies, C.; Villarreal-Ramos, B.; Wilson, T.; Beckmann, M. Oral supplement in healthy older adults to support physical fitness and mental wellbeing https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1563999/full (accessed May 23, 2025).
3. Krawiec, S. Standardized cucumber extract may support joint health according to a recent study https://www.nutritionaloutlook.com/view/standardized-cucumber-extract-may-support-joint-health-according-to-a-recent-study (accessed May 23, 2025).