Respiratory, immune health botanical ingredients to debut from Unigen at Natural Products Expo West 2022


The first ingredient, Attenutin, supports respiratory health. The second ingredient, Symetrian, is said to maintain healthy immune system homeostasis.

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Two new botanical ingredients, one for respiratory health and one for immune health, will debut from Unigen Inc. (Tacoma, WA) at next week’s Natural Products Expo West trade show in Anaheim, CA. The company will be exhibiting at booth #3775.

Attenutin is a new trademarked ingredient to support respiratory health. It contains two different types of bioflavonoids derived from the roots of Scutellaria baicalensis (also known as skullcap) and heartwood of Acacia catechu. The company says these ingredients are clinically proven to support innate and adaptive immunity while also supporting antibody IgA and IgG production and healthy cytokine levels.

Unigen’s CEO and Chief Science Officer Qi Jia, PhD, explained in a press release why the company decided to develop this ingredient. “Since early 2020, Unigen shifted its R&D focus to immune and respiratory health. We evaluated hundreds of bioflavonoids in our PhytoLogix library and historic data on maintaining a healthy level of an alarmin protein called HMGB1 that is proven to support and protect the immune function of the respiratory system.” The company says Attenutin was clinically shown to increase levels of glutathione peroxidase (GSH-Px) thanks to its strong antioxidant activity. It can be paired with ingredients like vitamin C and zinc for short-term use during immune-stressing seasons, the firm says.

The second ingredient, Symetrian, is a standardized composition of Aloe vera polysaccharides, Poria cocos sclerotium extract, and rosemary leaf extracts that is said to maintain healthy immune system homeostasis. The company says that Symetrian was clinically proven to promote the production of circulating TCRγδ+ gamma delta T cells, “suggesting its heightened immune surveillance at portals of entry.”

The company says in the press release: “Symetrian has been clinically shown to increase anti-oxidation capacity through elevated levels of glutathione peroxidase. In the second clinical trial of rapid immune modulation, a single oral dose showed progressive activation of lymphocytes (NKT cells, NK cells; cytotoxic T cells, γδ­‑T cells) over a three-hour period in the blood where the percent changes in activation were found [to be] statistically significant against placebo. Symetrian is suitable as a long-term dietary supplement year-round for all populations.”

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