NXT USA to showcase clinically validated ingredient portfolio at Natural Products Expo West 2026

Editor’s Note: this article has been updated on February 17, 2026 at 2:10pm to include an AI disclosure.

NXT USA is set to spotlight its portfolio of clinically validated nutraceutical ingredients at Natural Products Expo West 2026, taking place March 3–6 in Anaheim, California. Exhibiting in Hall D, Booth #4657, the Edison, NJ–based ingredient supplier will highlight science-driven solutions aligned with evolving formulation priorities across women’s health, digestive health, joint support, healthy aging, and metabolic wellness, a February press release from NXT USA explains.¹ Expo West attendees are invited to visit NXT USA to explore clinical data, formulation opportunities, and research programs supporting next-generation nutraceutical innovation, it adds.

NXT USA is positioning its portfolio around rigorous human clinical research paired with practical formulation benefits. According to the company, its Expo West presence reflects continued momentum for proprietary ingredients designed to deliver measurable outcomes at commercially viable doses. “We’re stoked to return to Expo West and connect with brands that are looking for differentiated, evidence-based ingredient solutions,” stated Todd Runestad, chief storytelling officer at NXT USA. “As consumer expectations rise, formulators need ingredients that deliver real-world results, supported by strong clinical validation.”

Xeya Modern Shatavari

Among the ingredients on display is Xeya Modern Shatavari, a low-dose, high-potency shatavari extract standardized for women’s hormonal balance across life stages. The ingredient has been evaluated in two published human clinical trials demonstrating hormone-balancing effects (demonstrated in a randomized, double-blind, placebo-controlled clinical trial published in Food & Nutrition Research December 2025²) and benefits related to reproductive and perimenopausal health, including improvements in hot flash frequency (shown in a randomized, double-blind, placebo-controlled study published in Functional Foods in Health and Disease in July 2025³).

Additional studies are underway examining menstrual quality of life, stress, sleep, fatigue, and bone mineral density, in healthy young women.

BluNAD Booster

NXT USA will also feature BluNAD Booster, a plant-based ingredient formulated to support healthy aging by both increasing and preserving nicotinamide adenine dinucleotide (NAD+) levels. Rather than focusing solely on NAD+ production, BluNAD targets CD38 enzymes that degrade NAD+. A December 2025 published study published in the Journal of Functional Foods reported greater NAD+ increases compared to the NAD+ precursor nicotinamide riboside (NR).⁴ The trial included 140 healthy and aging adults, who received either 1000 mg of BluNAD Booster, 500 mg of NR, a combination of 500 mg of BluNAD Booster and 500 mg of NR, or a placebo for 60 days, with results also demonstrating improvements in cognitive performance, physical endurance, and energy.

Digexin

Digestive health solutions tailored to the GLP-1 landscape will be another focus at the booth. Digexin, an herbal formulation positioned as a “relaxative,” has been studied in both healthy individuals and GLP-1 users, with data showing support for digestive regularity within seven days. The ingredient earned Ingredient Idol recognition at SupplySide West 2023 for its microbiome-focused innovation. Additionally, in November 2025, NXT USA announced Digexin has received independent third-party substantiation of their claims from US regulatory compliance firm REJIMUS, Inc.⁵

TamaFlex

Rounding out the portfolio is TamaFlex, a joint health ingredient supported by multiple human clinical studies demonstrating noticeable joint comfort in as few as five days, along with longer-term structural benefits. One study, published in Food & Nutrition Research in 2023, also demonstrated significant reductions in WOMAC scores from 250 mg of Tamaflex for 30 days, as well as improvements in musculoskeletal function compared to baseline and placebo, with improvements in knee pain and musculoskeletal function.⁶

Underlying NXT USA’s product development strategy is its “4 Pillars of Validation” framework, which integrates patient-reported outcomes, physician assessments, biomarker analysis, and physical measurements. This multi-layered approach is designed to provide brands with both scientific credibility and consumer-relevant results.

This article was created with assistance from AI. The content has been reviewed and edited by Erin McEvoy, Associate Editor. For more information on the extent and nature of AI usage, please contact us.

References

1. NXT USA. NXT USA to Exhibit Science-Driven Ingredient Innovations at Natural Products Expo West 2026. February 3, 2026.
2. Kondamudi, S.; Sadu, S.; Deva, S.; Yalamanchi, A.; Yalamanchi, A. CL22209, a standardized Asparagus racemosus root extract, demonstrates improved ovarian morphology, menstrual regularity, and metabolic parameters in women with polycystic ovary syndrome in a randomized, controlled trial. Food & Nutrition Research. 2025. 69: 13244. DOI: 10.29219/fnr.v69.13244.
3. Yadav, P.; Yadav S.; Vedururu SS.; Kumari, G. Clinical assessment of CL22209, a standardized proprietary extract of Asparagus racemosus, for mitigating vasomotor and menstrual symptoms in perimenopausal women: A randomized, double-blind, placebo-controlled study. Functional Foods in Health and Disease 2025; 15(7): 415 - 443. DOI: DOI: 10.31989/ffhd.v15i7.1684
4. Bandi, V.K.; Chundru, V.K.; Yarasani, A.; Gajula, R.; Pulipaka, V.K.; Syed, T. Comparative efficacy of a standardized herbal composition LN22199, nicotinamide riboside, and their combination on NAD+ metabolism in healthy aging adults, Journal of Functional Foods, 2025. 135. DOI: 10.1016/j.jff.2025.107115.
5. Colli, M. Digexin digestive regularity claims confirmed by third-party regulatory compliance firm. November 24, 2025. https://www.nutritionaloutlook.com/view/digexin-digestive-regularity-claims-confirmed-by-third-party-regulatory-compliance-firm (Accessed 2026-02-17).
6. Kraweic, S. Joint health supplements poised for mainstream acceptance. September 16, 2025. https://www.nutritionaloutlook.com/view/joint-health-supplements-poised-for-mainstream-acceptance (Accessed 2026-02-17).