Science

A new 12-week trial adds controlled data to a question that matters for manufacturers positioning creatine beyond sports nutrition: does its muscle-building evidence hold up in adults over 45, including those not following a structured exercise program?

A randomized, crossover trial found that ThymoDream, a standardized black cumin seed oil, raised endogenous melatonin levels and improved several sleep measures over 7 nights, with lower reported daytime sleepiness than synthetic melatonin.

Piping Rock Health Products has launched a 300-mg NMN gummy under its Vitafusion brand, arriving less than a year after the FDA reversed its position on whether the ingredient could legally be sold as a dietary supplement.

The Indian branded-ingredient supplier has closed a growth investment from NDude Labs to expand clinical research and establish a dedicated US commercial operation, reflecting investor interest in ingredient companies that lead with published data.

A mixed cell-culture and mouse study found that Ahiflower oil, a plant-based omega-3 source, reduced markers of endothelial inflammation, blood lipids, and platelet clotting activity at levels comparable to fish oil.

Pooled RCT evidence from three EU consortia shows non-nutritive sweeteners may support weight loss maintenance without adverse effects on biomarkers or taste preference.

The randomized, double-blind placebo-controlled study found laboratory safety markers remained within normal ranges across treatment and placebo groups.

A 28-day evaluation of TriNutra’s 5% B'utyQuin scalp lotion reported reduced hair loss and modest density increases in 22 adults, adding early clinical data to a cosmetic ingredient formulators are positioning for scalp health claims.

Why do promising nutraceutical ingredients underperform in human trials? This piece explores how phenotype-based recruitment aligns participant biology with mechanism, reducing signal dilution and producing more commercially meaningful efficacy evidence.

The comprehensive review synthesizes mechanistic and clinical evidence on the probiotic strain's role in enhancing non-heme iron absorption.

New preclinical research on Elissara by Monteloeder, SL, point to multiple mechanisms of action for the four-botanical ingredient, examining effects on DHT-related enzymes, cell proliferation, and oxidative stress.

A placebo-controlled study on Ixoreal's standardized root extract points to reductions in hot flashes, stress, and mood symptoms after eight weeks of supplementation.

A new double-blind trial reports metabolic and cognitive benefits in midlife women, building on the brand's expanding clinical trial program and recent $27M investment.

The Centrum-focused ISMOS study aims to fill a data gap in an underrepresented population, following prior research on vitamins and metabolic syndrome risk.

Results from the 12-week clinical trial link a targeted probiotic formula to measurable improvements in menopausal symptoms and quality of life.

Clinical trial finds 200 mg of bio-optimized berberine improves blood glucose, GLP-1, and lipid markers at doses lower than conventional berberine.

Essential vitamins and minerals for bone health are expanding beyond single-nutrient formulations to target complex support for broader demographics.

Researchers propose a dual-nutrient strategy for cardiovascular health, detailing how potassium chloride can complement sodium reduction.

Daily almond consumption over 5 months demonstrated improvements in sleep efficiency and sleep continuity in adults with poor sleep.

A new randomized, placebo-controlled trial examined the combined botanical's effects, finding support for hot flashes, sleep, mood, and hormone levels.

A randomized, placebo-controlled trial found that daily fucoidan supplementation improved urinary symptoms and quality of life in men with moderate benign prostatic hyperplasia (BPH).

Cost-driven decisions in nutraceutical clinical trials can affect more than budgets — they can determine whether your evidence supports real product claims. Here is a look at where the risks lie.

Eurofins Lab results show four newly tested products containing a fraction of their labeled ubiquinol content, bringing the total number of flagged ubiquinol products to two dozen.

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Cross-sectional data from over 2,000 older adult participants show vitamin C status correlated with brain volume and connectivity.