Nexira’s Inavea acacia fiber improved constipation symptoms in IBS patients, new unpublished study shows


The company says this is the first study showing that acacia fiber can benefit transit modulation in adults.

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A new study in irritable bowel syndrome (IBS) subjects, not yet published, showed that Nexira’s (Rouen, France) Inavea pure acacia prebiotic fiber helped improve constipation symptoms. The company says this is the first study showing that acacia fiber can benefit transit modulation in adults.

The double-blind, placebo-controlled study was conducted on 120 subjects who were predominantly suffering from constipation due to IBS. Subjects were given 10 g of Inavea acacia fiber, or a placebo, for four weeks. The company says Inavea subjects saw significantly improved constipation symptoms following the intervention.

“It was the first time that acacia fiber has demonstrated its benefit on transit modulation in adults,” said Damien Guillemet, Nexira’s scientific director, in a press release.

The new study also showed benefits for a secondary endpoint of digestive comfort. “Nexira has previously demonstrated that acacia fiber is highly tolerable, especially compared to FOS,” Guillemet said. “The interesting point of this latest study is that Inavea pure acacia was compatible with [the] IBS population, [who are] known to be highly sensitive.”

Julie Impérato, Nexira’s marketing manager, added, “One of the most important threats for fiber intake is the associated digestive discomfort. That said, these results supporting digestive comfort are certainly a major asset for Inavea pure acacia.”

She said that constipation and transit are still important topics in digestive health. “Talking about constipation or transit seems to be old-fashioned in front of the microbiome, -biotics, and so on. However, with more than 40% of people worldwide suffering from a functional gastrointestinal disorder, this solution to improve transit still has a huge potential for supplement manufacturers.”

Inavea is suited for supplement, powders, and functional foods and beverages.

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