Success for NEM in Simulated Digestive System

December 22, 2011

The company says that NEM significantly reduced the levels of several compounds-a reduction that was further improved when NEM was sent through a simulation of the human digestive system.

The folks at ESM Technologies (Carthage, MO) are pleased to report the completion of an in vitro study on Natural Eggshell Membrane (NEM) and the human digestive process. Their research further supports NEM as a potential supporting dietary supplement for joint pain and stiffness.

NEM is a GRAS ingredient produced from eggshell and containing natural amounts of glycosaminoglycans, such as chondroitin sulfate and hyaluronic acid.

Published online at the Journal of Medicinal Food, the study involved exposing human immune cells to a water extract of NEM and pro-inflammatory compounds. The company says that NEM significantly reduced the levels of several compounds-a reduction that was further improved when NEM was sent through a simulation of the human digestive system. Take a look at what the company reported regarding NEM’s effect on one of those key cytokines, tumor necrosis factor (TNF)-alpha:

“Where the crude product suppressed the inflammatory cytokine TNF-alpha production in cultures of human immune cells, the NEM after an in vitro digest produced similar effect at 100 times lower doses, suggesting stronger anti-inflammatory effects after digestion.”

ESM Technologies considers this demonstration as a reflection of the process that would occur in the actual human body. For more information on the study and NEM for joint health, visit ESM Technologies online.