Study Says Artinia Lowers Oxidized LDL Cholesterol

September 19, 2012

Oxidized LDL cholesterol is a risk factor for heart disease.

Stratum Nutrition’s (St. Louis) chitin-glucan ingredient Artinia may lower oxidized LDL cholesterol in humans, according to a study published in the European Journal of Clinical Nutrition.

Oxidized LDL cholesterol is cholesterol that has been exposed to high levels of free radicals. Evidence suggests that this form of cholesterol can greatly increase one’s risk of atherosclerotic heart disease.

In a six-week human clinical trial, researchers (including Stratum personnel) assigned 130 human subjects to six weeks of supplementation with Artinia, Artinia and olive oil extract (potentially anti-inflammatory), or placebo. All subjects reported in with borderline or high LDL levels.

At the end of the study, daily Artinia supplementation was deemed effective at lowering oxidized LDL cholesterol over placebo-in a high dose (4.5 g) or a low dose (1.5 g)-but the effect was only significant with the low dose. Artinia didn’t significantly affect HDL cholesterol, triglyceride, insulin or glucose levels in subjects.

Stratum pharmacology manager and coauthor of the study Joseph L Evans, PhD, said the study findings complement previous work performed on animal models.