
Natural Insect Repellent Ingredients
Key Takeaways
- CDC recommends using EPA-registered repellents containing one of six specified active ingredients, including DEET and picaridin, for mosquito-bite prevention.
- Two plant-derived actives, oil of lemon eucalyptus (OLE) and 2-undecanone, are included among the recommended EPA-registered options.
Fun Fact! The CDC lists oil of lemon eucalyptus (OLE) and 2-undecanone as plant-derived ingredients that can be found in EPA-registered insect repellents.
Fun Fact! For repelling insects, the U.S. Centers for Disease Control and Prevention recommends using EPA-registered repellents that include 1 of 6 active ingredients, and among this list are 2 plant-derived ingredients. Oil of lemon eucalyptus (OLE) and 2-undecanone sit alongside synthetics like DEET and picaridin.
The CDC does note that it does not know the effectiveness of non-EPA-registered repellents, including some natural repellents.
Source: Centers for Disease Control and Prevention. Preventing mosquito bites. CDC Mosquitoes. Reviewed August 28, 2024. Accessed August 11, 2026.





