Comet Bio announces positive results of study evaluating tolerability of its prebiotic Arrabina

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Comet Bio (Schaumburg, IL) has announced the results of an unpublished randomized placebo-controlled, crossover clinical trial evaluating the gastrointestinal tolerability and prebiotic effects of its Arabinoxylan Plant Fiber Extract, Arrabina. In the study, 44 healthy subjects consumed either 6 grams, 12 grams, or placebo daily for three weeks. Subjects ranked eight areas of gut and bowel discomfort including gas, bloating, and nausea to provide comparison in GI tolerance of the three treatments. While prebiotics are important for feeding the microbiome, many prebiotic products on the market are associated with GI distress and bloating, making it difficult for consumers to incorporate into their daily lives.

The results of the study showed that in the areas of gut and bowel discomfort, there were no stratistical differences between the Arrabina groups and placebo, which means that the prebiotic was well tolerated and did not cause GI distress in subjects. "We are thrilled that the clinical trial results prove that ArrabinaTM is exceptionally well-tolerated," said Andrew Richard, CTO of Comet Bio, in a press release. "These results add to the body of the clinical evidence we have assembled, including structure-function claims that our Arabinoxylan Plant Fiber Extract, Arrabina is a prebiotic that helps maintain healthy blood sugar and supports immunity."

Arrabina is upcycled from crop leftovers, such as leaves, stalks, and shells, allowing farmers to use their whole harvest and prevent food waste. "Our proprietary water extraction technology makes it possible to produce Arabinoxylan and other nutrition from upcycled crop leftovers," said Comet Bio CEO, Rich Troyer, in a press release. "Our process uses water and pressure to produce Arabinoxylan as a fully-soluble powder with superior functionality. Arrabina’s low viscosity means it will not gel or impact texture when added as a supplement to protein powders or as a fiber boost for nutrition bars, baked goods, and drinks."