Inside Out Wellness: Supplements for Every System

During SupplySide Global 2025, Drs Edward Dosz and Michael Lelah, of NutriScience Innovations, shared the latest science behind several clinically supported ingredients advancing cardiovascular, digestive, and cognitive wellness.

They began with a brief discussion about NiaXtend®, an extended-release nicotinic acid (niacin) shown in clinical studies to lower LDL and triglycerides while raising HDL cholesterol—an outcome not typically achieved by statins. Newer research also highlights its ability to boost NAD⁺, a coenzyme vital for cellular energy and DNA repair, offering direct support for cardiovascular and healthy aging benefits.

Next, they discussed PepZin GI®, a zinc–L-carnosine complex clinically proven to protect and repair the gastrointestinal lining. Studies show it supports natural mucosal healing, reduces inflammation, and alleviates symptoms such as heartburn and IBS.

Dr Dosz then detailed ButyraGen®, a next-generation butyrate generator delivering targeted gut health benefits independent of microbiome composition. A recent clinical study reported improved digestive comfort and reduced abdominal pain—especially among postmenopausal women—with emerging data linking ButyraGen® to enhanced gut-brain communication and emotional well-being.

Finally, the experts commented on Suntheanine®, the original and most studied form of L-theanine, which stands out for its purity, consistency, and safety. Supported by more than 50 human clinical trials, Suntheanine® has demonstrated benefits for relaxation, focus, stress reduction, and sleep quality—often within 30–45 minutes.

Together, explained the Drs Dosz and Lelah, these ingredients exemplify how NutriScience Innovations combines clinical validation and targeted nutritional science to support heart, gut, and brain health.