L-Citrulline Now GRAS for Food, Beverage
By increasing nitric oxide production, L-citrulline helps promote vascular dilation and healthy blood circulation.
Kyowa Hakko USA’s (New York City) L-citrulline can now be used in food and beverages. The company has self-affirmed the amino acid as Generally Recognized as Safe.
By increasing nitric oxide production, L-citrulline helps promote vascular dilation and healthy blood circulation. It is converted to L-arginine and nitric oxide in the body. Additionally, L-citrulline helps relieve muscular fatigue by eliminating ammonia, the company says. Other possible benefits include antioxidant activity and heart protection.
As a food ingredient-backed by Kyowa Hakko’s quality seal-L-citrulline is deemed safe for use at a dose of up to 275 mg/serving and up to a maximum of 2000 mg/day. It can be used in beverages and beverage bases, grain products and pastas, milk products, and more.
HHS announces efforts to eliminate independent conclusion of GRAS
Published: March 11th 2025 | Updated: March 11th 2025U.S. Department of Health and Human Services (HHS) Secretary, Robert F. Kennedy Jr., is directing the acting U.S. Food and Drug Administration’s (FDA) acting commissioner to explore rulemaking that would eliminate the independent conclusion of GRAS provision.
