Target Practice: Matching Strain to Symptoms
Getting probiotic supplementation right is all about targeting the strain to the concern—whether that’s gut health and immunity or metabolic health, mood, and weight management.
And as Allie Chandler, head of brand and head of B2B marketing, Novozymes OneHealth North America (Franklinton, NC), says, “Within the context of the gut microbiome, there are keystone species that play crucial roles in maintaining the structure and function of the microbial community and that can have profound impacts on host physiology—including on weight and metabolic health.”
Here are some of her top picks, and why:
Feeds on the mucin layer of the gut, which can stimulate the production of new mucin, maintaining a healthy gut barrier.
Higher levels of A. muciniphila have been associated with improved glucose homeostasis and reduced adipose tissue inflammation (lower levels associated with obesity and type 2 diabetes).
It’s a major butyrate producer, which is a short-chain fatty acid that serves as an energy source for gut cells and has anti-inflammatory properties.
Lower levels of F. prausnitzii have been linked to conditions like inflammatory bowel disease, obesity, and type 2 diabetes.
This bacterium is involved in carbohydrate fermentation and the production of short-chain fatty acids.
Through its activity, it helps maintain gut barrier function, modulates immune responses, and impacts energy extraction from the diet.