News|Articles|October 17, 2025

Butternut squash hands

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Key Takeaways

  • Butternut squash can cause hand dermatitis, presenting as dryness and itchiness on the palms due to an unknown irritant.
  • The specific irritant causing this reaction remains unidentified, necessitating further research to understand the underlying mechanisms.
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Fun fact! Butternut squash contains an unknown irritant that for some people may cause dryness and itchiness on their palms when processing the vegetable.

Butternut squash contains an unknown irritant that for some people may cause dryness and itchiness on their palms when processing the vegetable.

Source: Shah, M.A.; Feldman, S.R. Hand Dermatitis Secondary to Exposure to Butternut Squash. Case Rep Dermatol. 2022, 14 (2), 123-126. DOI: 10.1159/000524930

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