Recent study demonstrates endurance, strength, and recovery benefits of branded dual polyphenolic ingredient, Gremin

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Zeus Hygia Lifesciences announced a newly published study in their recent press release which detailed that the dual polyphenolic ingredient (PDPI) called Gremin may help with extending with extending endurance, shorter recovery times, and greater strength. The ingredient combines coffee bean extract and curcumin.

The clinical study was published in Fortune Journal of Health Sciences and sought to investigate what effects PDPI could have on fatigue, isometric muscle strength, and endurance. To gather research, 60 participants were selected, and then were split into two groups. One group received 500 mg PDPI, and the other group received a placebo over the course of 14 days. Both groups were evaluated through physical fitness.

As the data came in, researchers saw improvements with endurance, recovery, and fatigue in the group that received 500 mg of PDPI when compared to the placebo group.¹ To measure endurance, researchers had participants perform a six-minute walking test. For muscle strength, this was measured by an isometric muscle strength study which showed that muscle strength had improved. Fatigue was measured with an MFI questionnaire. Additionally, participants in the PDPI group experienced gains in fat-free mass and lean body mass when compared to baseline.¹

The study authors concluded¹, “The present clinical evidence highlights the effectiveness of Gremin in significantly enhancing endurance, improving muscle performance, and providing robust muscle protection, making it a potential supplement for athletes and active individuals looking to elevate their physical performance and recovery.”

Arun Kanth, PhD, co-founder and director, Zeus Hygia Lifesciences, commented in the press release, “This study underscores the value of Gremin as a multi-functional fitness-enhancement supplement. Moreover, consumers can feel and see its clinically proven benefits in only 14 days, as shown by the researchers.”

In particular, the study highlights the connection between enhancing endurance and protecting muscles. According to the study's authors, “Endurance, muscle performance, and muscle protection are closely interconnected,”.¹ Muscle performance is supported with endurance because it helps muscles to contract optimally as they tire. In regard to muscle protection, It helps assist muscles in not becoming overly strained throughout prolonged activity. “Together, these three elements enable athletes and active individuals to perform at their best, recover effectively, and reduce the risk of injury,” the authors write.

For more information on Gremin, please click here.²

References

1. Shankaranarayanan Jeyakodi, Arunkanth Krishnakumar, Mohan Muttanahally Eraiah, Jestin V. Thomas, Lincy Benzy Joshua. A Proprietary Dual Polyphenolic Ingredient for Endurance, Muscle Performance, and Muscle Protection in Healthy Subjects: A Randomized, Double-Blind, Placebo- Controlled, Parallel-Group Clinical Study. Fortune Journal of Health Sciences. 2024. 7: 602-614. https://cdn.fortunejournals.com/articles/a-proprietary-dual-polyphenolic-ingredient-for-endurance-muscle.pdf
2. Muscle recovery endurance and performance https://gremin.zeushygia.com/ (accessed Apr 30, 2025).