IPA announces adoption of ISAPP’s prebiotic definition

In a recent press release¹, the International Probiotics Association (IPA) revealed that the organization has adopted the 2017 prebiotic definition from the International Scientific Association for Probiotics and Prebiotics (ISAPP).

The definition is listed as “A substrate that is selectively utilized by host microorganisms conferring a health benefit.”¹ The IPA first began in 199 and has been a trusted platform for the probiotics industry. The organization expanded their initiatives to include synbiotics, prebiotics, and postbiotics.¹

Aside from the addition of the ISAPP prebiotic definition, the IPA Board has formed a Prebiotic Definition Task Force. This group will consist of industry and scientific leaders from IPA member companies and will “evaluate existing prebiotic definitions using scientific, commercial, regulatory, and communication criteria.”¹ So far, the Task Force has orchestrated a thorough survey of IPA members, as well as a structured assessment. With these materials, the IPA was suggested to adopt the ISAPP definition.¹

According to the press release, IPA adopted the definition for the reasons listed below:¹

1. It is supported by extensive scientific research and provides good alignment for scientific substantiation.
2. It emphasizes microbial selectivity and acknowledges microbiome benefits. It allows for future accommodation of evolving science and novel prebiotics including extending the prebiotic concept beyond the gut.
3. It reinforces clinical relevance and provides a scientific basis for regulatory decision-making.

Through the acceptance of the recent ISAPP definition, IPA puts the organization in a stronger position as “The Global Voice of Pre-, Pro-, and Postbiotics.”¹

“This is not just a definition, it is a strategic commitment to clarity, integrity, and progress in the prebiotic space. Alignment with the ISAPP prebiotic definition will enhance consistency in how prebiotics are understood, communicated, and developed across sectors.” said George Paraskevakos, Executive Director, IPA.¹ “With strong consensus from our membership and scientific partners, IPA remains committed to serve as a trusted steward and global leader for the responsible evolution of the biotics field.”

“A common understanding of the term ‘prebiotic’ is critical for advancing scientific research, developing effective and evidence-based products, and ultimately making it easier for consumers to access the health benefits that prebiotics can provide. Having more voices behind the same message will help to further align and inform stakeholders in these endeavors,” mentioned Marla Cunningham, Executive Director of ISAPP.¹ “We're pleased to hear of IPA's support, and we look forward to further positive progress in prebiotic implementation as a result.”

Reference

1. https://internationalprobiotics.org/home/the-ipa-adopts-isapps-prebiotic-definition-2/ (accessed May 29, 2025).