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A recent study published in the European Journal of Nutrition demonstrates that the patented self-micro-emulsifying delivery system (SMEDS) called AquaCelle improves that absorption of omega-3 fatty acids EPA and DHA.
A recent study published in the European Journal of Nutrition demonstrates that the patented self-micro-emulsifying delivery system (SMEDS) called AquaCelle (from Pharmako Biotechnologies, based in New South Wales, Australia) improves that absorption of omega-3 fatty acids EPA and DHA. In the randomized, double-blind, participants were given a single 680 mg dose of omega-3 ethel esters (EE) containing 272 mg of EPA EE and 204 mg of DHA EE. One group took the omega-3 dose with SMEDS, and the other without (control).
Results showed that combining the omega-3 EE with SMEDS caused instant and complete emulsification on addition to water, while the control fish oil did not emulsify. In subjects, the group taking fish oil with SMEDS experienced a 3.7 and 7.1-fold increase in omega-3 maximum plasma concentration and absorption, respectively, compared to placebo.
“It is commonly known that omega-3 absorption is best achieved with a high-fat meal. However, because many individuals require low-fat diet restrictions, oral bioavailability is incomplete, and requires higher doses,” said George Kokkinis, co-founder/technical director at Pharmako Biotechnologies, in a press release. “This study highlights the superiority of AquaCelle as a delivery system for significantly improved absorption of lipophilic ingredients.”
A previous study demonstrated that AquaCelle can improve the absorption of CoQ10.
1. Bremmell KE et al. “A self-emulsifying Omega-3 ethyl ester formulation (AquaCelle) significantly improves eicosapentaenoic and docosahexaenoic acid bioavailability in healthy adults.” European Journal of Nutrition, Published online ahead of print on October 21, 2019