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What’s the best way to ensure a GRAS notification for an ingredient’s use in medical foods will receive a “No Questions” letter from FDA?

Medical Foods: Creating a Successful GRAS Notification

 and reminds us to soak in all the amazing achievements women have made to the nutraceutical space.

 is putting the spotlight on women by compiling women-related content, new and old. From research to health and wellness, women are such an important part of the nutraceutical space that 

is dedicated to covering closely. Enjoy International Women’s Day 2025!

Read more on women-led omega-3 research advances wellness for all women’s life stages.

Highlighting research on women's health and wellness, part I

In this compilation, we present recent research on menstruation and skin health. Check out studies on pain management, natural supplements for skin appearance, and even stress and sleep support.

Celebrating International Women's Day: Highlighting research on women's health and wellness, Part II

In the second part of our research spotlight, we present recent research on pregnancy and menopause.

To celebrate International Women's Day (March 8) we are highlighting articles and roundtables, produced in partnership with Women in Nutraceuticals, on women’s health research and the role of women leaders driving innovation and equity in the industry.

Stay tuned for more International Women's Day-themed content! We will be updating this landing page throughout this week.

International Women’s Day. International Women’s day 2025 campaign theme: Accelerate action 

Check out our exciting 2025 International Women's Day coverage!

Women In Nutraceuticals

Topic

Nutritional Outlook celebrates International Women's Day 2025

OmniActive Health Technologies (Bridgewater, NJ and Mumbai, India) has announced a partnership with the Council for Responsible Nutrition (CRN; Washington, D.C.) to educate and raise awareness about the role of lutein and zeaxanthin in supporting maternal and fetal health during pregnancy among obstetricians, gynecologists, and other maternal healthcare practitioners. This knowledge will be shared at The American College of Obstetrics and Gynecology’s (ACOG) Annual Clinical & Scientific Meeting. OmniActive is 

one of six companies CRN has partnered with

 to showcase the latest research and developments in prenatal nutrition through a specially designed “Prenatal Nutrition Center” at the conference. 

“It’s wonderful to have OmniActive as one of our featured partners during the ACOG annual event to help spread the word on the importance of prenatal nutrition,” said Andrea Wong, PhD, senior vice president, Scientific & Regulatory Affairs for CRN, in a press release. “CRN continues our efforts in supporting supplement manufacturers and ingredient suppliers in bringing clinically studied products to consumers to help meet their nutritional needs. Advancing awareness at the physician’s level is a huge part of this equation and this meeting is an effective way of reaching them.”

Citing market research from SkyQuest Technology, OmniActive explains in its press release that prenatal supplement sales were estimated to be at $740 million in 2023 and projected to rise to $1.4 billion by 2031. Similarly, a recent 

 found that about 60% of gynecologists think that 80-100% of their pregnant patients take dietary supplements. There is therefore a great deal of opportunity to grow and advance this category. Lutein and zeaxanthin are known for their support of eye health, but these benefits are relevant during pregnancy as well, says Deshanie Rai, PhD, FACN, vice president of Global Science, Regulatory and Advocacy at OmniActive Health Technologies.

“Current evidence supports the preferential accumulation of lutein and zeaxanthin in the human eye and neural tissues during pregnancy, especially during the third trimester. This suggests that lutein may play a functional and protective role in infant visual and cognitive development. As part of our Lutein for Every Age campaign, our goal is to help educate healthcare practitioners on this latest nutritional science research and the benefits of achieving adequate dietary lutein during pregnancy,” said Rai, in a press release. “OmniActive is proud to partner with the CRN Foundation’s Prenatal Nutrition Centre to promote awareness among healthcare practitioners on the nutritional relevance of lutein for both mom and baby.”

The educational initiative, “Lutein for Every Age,” focuses on raising awareness of early and consistent lutein and zeaxanthin intake to help support eye, cognitive, and general health throughout life, explains OmniActive. The AOCG meeting is taking place from May 17-19, 2024 in San Francisco, CA.

OmniActive Health Technologies has announced a partnership with the Council for Responsible Nutrition to educate and raise awareness about the role of lutein and zeaxanthin in supporting maternal and fetal health during pregnancy among obstetricians, gynecologists, and other maternal healthcare practitioners. 

OmniActive partners with CRN to raise awareness about macular carotenoids for prenatal health

Help companion animals keep up with their owners: Discover the science behind UC-II® undenatured type II collagen

, the nonprofit Institute for the Advancement of Food and Nutrition Sciences (IAFNS) announced the release of reference material (RM) for gut microbiome research from U.S. National Institute of Standards and Technology (NIST). As noted in the press release, the lack of samples available for comparison and issues with the reproducibility of results provides a challenge for laboratories and inhibits research. The reference material was created with support from the IAFNS Nutrition for Gut Health Committee and is intended to support the progress of human health and disease research.

“We hope our reference material will lay the foundation for gut microbiome research to thrive and reach its full potential,” stated NIST molecular geneticist Scott Jackson, in a March 17 

. “We’re moving toward a time when we can all agree on exactly what we’re talking about when we’re discussing the human gut microbiome.”

As the press release explained, gut microbiome activity has been linked with various conditions and diseases including obesity, diabetes, mental illness, and cancer, and that targeting the gut microbiome with a new class of drugs can also target the conditions.

A November 2024 study partially supported by the IAFNS Gut Health Committee assessed human stool samples (from vegan and omnivore donors to ensure a range of variability

) as candidates to be used as for the reference material. The study involved 18 institutions using various preferred analytical techniques, defined chemical fingerprints for the cohorts, and resulted in the development of two microbiome stool sample reference materials, “RM 8048 Human Fecal Material,” available from NIST in eight 100-milligram tubes along with information on the microbes and metabolites

“This collaborative exercise emphasized the broad chemical survey possible with multi-technique approaches,” researchers stated in the study’s conclusion. “Community engagement is essential for the evaluation and characterization of common materials designed to facilitate comparability and ensure data quality underscoring the value of determining current practices, challenges, and progress of a field through interlaboratory studies.”

Additionally, NIST is also working on “RGTM 10212 Fecal Metabolite Mixture,” aiming to validate the performance of laboratory instruments.

IAFNS will hold a webinar on April 29, 2025, to host NIST explaining more information on the reference material.

Institute for the Advancement of Food and Nutrition Sciences. New Gut Microbiome Reference Material Set to Transform the Field 

https://www.newswise.com/articles/new-gut-microbiome-reference-material-set-to-transform-the-field

National Institute of Standards and Technology. NIST Releases Reference Material to Aid Gut Microbiome Research 

https://www.nist.gov/news-events/news/2025/03/nist-releases-reference-material-aid-gut-microbiome-research

 Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors. 

The reference material is intended to support the standardization of research on the human gut microbiome to help reduce disease risk.

National Institute of Standards and Technology releases reference material for gut microbiome research

Nutritional Outlook talks to ADM's June Lin at Expo West about their latest postbiotic ingredient.

Innovations in postbiotics with ADM

Nutritional Outlook talks to ADM's vice president of global marketing and innovation, June Lin, at Expo West about the company's latest postbiotic ingredient.

Nutritional Outlook talks to Cargill's Jana Mauck about the company's recent report on consumer snacking behavior.

Ginny Banks

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