Plantain Extract to Target Crohn’s Disease

May 13, 2011

UK-based ingredient supplier Provexis says it is developing a plantain-derived extract that may provide support for Crohn’s disease patients during remission.

UK-based ingredient supplier Provexis says it is developing a plantain-derived extract that may provide support for Crohn’s disease patients during remission.

“The new ingredient, which comes from a fiber found in plantain, works by inhibiting the interaction between Escherichia coli bacteria often found in Crohn’s disease patients and cells lining the intestine,” the company says. “As E. coli bacteria have been found to interrupt a number of immunological interactions, their inhibition could potentially have a range of therapeutic benefits for the patient.”

The company says it is currently conducting a randomized controlled study to examine the effects of the extract in maintaining remission in Crohn’s disease patients at four centers in the UK. It says that preliminary trials in healthy humans showed no significant adverse effects on markers of gastrointestinal health over a 21-day supplementation period.