New Berry Polyphenol Ingredient Designed to Improve Memory


The new Memophenol ingredient from Activ’Inside combines French grape and wild blueberry extracts.

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Activ’Inside (Libourne, France) has launched a new berry polyphenol ingredient that it says is designed to improve learning, working memory, and long-term memory performances. The new cognitive-health ingredient combines French grape (Vitis vinifera) and wild blueberry (Vacciniumangustifolium) extracts.

The patent-pending ingredient made its debut at the recent Vitafoods Europe trade show, with several recent studies supporting its potential benefits for brain health. Most recently, an animal study published in Frontiers in Behavioral Neuroscience1 suggested that the same berry polyphenols found in Memophenol may improve memory and spatial learning in mice.

The ingredient has also been evaluated in a bi-center, randomized, double-blind, placebo-controlled clinical study of more than 200 people over the course of six months. Compared to a placebo group, participants consuming Memophenol forgot 2.5 times fewer words, made 2 times less memory errors after 6 months of supplementation, and presented cognitive test scores signifying a brain age up to 10 years younger, according to Activ’Inside. Participant cognitive function was assessed with a verbal recall memory test and a paired associated learning test.

Memophenol is appropriate for nutraceutical and food applications at a dose of 300 mg oral supplementation once or twice per day. Activ’Inside says the solution is designed for age groups ranging from teenagers to seniors, whether consumers are looking “to improve their learning and memory performances or prevent the onset of age-related cognitive decline.”


Read more:

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Michael Crane
Associate Editor
Nutritional Outlook Magazine


1.     Bensalem J et al., “Dietary polyphenol supplementation prevents alterations of spatial navigation in middle-aged mice,” Frontiers in Behavioral Neuroscience, vol. 10 (February 2016): 9

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