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The KSM-66 group also demonstrated a 27.9% reduction in serum cortisol levels.
KSM-66 ashwagandha significantly reduces stress and cortisol levels, according to a new study published in the Indian Journal of Psychological Medicine. KSM-66 is an ingredient from supplier Ixoreal Biomed Private Ltd. (Hyderabad, India).
In the 60-day, double-blind, randomized, placebo-controlled trial, 64 subjects with a history of chronic stress were given either a placebo or one capsule containing 300 mg of KSM-66 extract.
During the trial, subjects were evaluated using psychometric measurements, including the Perceived Stress Scale (PSS), the General Health Questionnaire-28 (GHQ-28), and the Depression Anxiety Stress Scale (DASS). The GHQ-28 stress measurement showed a 72.3% reduction in stress from baseline; the DASS showed a 71.6% reduction; and the PSS showed a 44% reduction.
Researchers said that on the whole, the KSM-66 group experienced improved relaxation, mental calmness, sleep, and productivity. The KSM-66 group also demonstrated a 27.9% reduction in serum cortisol levels.
“This study examined how KSM-66 functions as an adaptogen assisting the body in producing a normalizing effects for reducing stress and anxiety,” says Kartikeya Baldwa, director of Ixoreal Biomed.