A recent study found that supplementation with 5-methyltetrahydrofolate as Quatrefolic from Gnosis by Lesaffre and a vitamin B complex containing vitamin B12 and B6 had a positive impact on pregnancy outcomes in infertile women undergoing Assisted Reproductive Technologies.
A recent study published in the International Journal of Environmental Research and Public Health1 found that supplementation with 5-methyltetrahydrofolate as Quatrefolic from Gnosis by Lesaffre (Marcq-En-Baroeul, France) and a vitamin B complex containing vitamin B12 and B6 had a positive impact on pregnancy outcomes in infertile women undergoing Assisted Reproductive Technologies. In the retrospective study, 111 women took Quatrefolic and vitamin B complex daily (group A) while 158 women only took a daily dose of folic acid (group B). Results showed that women in group A had a higher percentage of clinical pregnancy (60.4% vs 44.9% in group B) and live birth (48.6% vs. 35.4% in group B).
“We are excited to see the increasing volume of publications related to the role of the biologically active form 5-MTHF as a better option than folic acid in fertility problems and pregnancy outcomes,” says Silvia Pisoni, global market manager of reproduction and women’s health with Gnosis by Lesaffre, in a press release, noting that this study strengthens the positioning of Quatrefolic in fertility, validating results from previous studies. “Quatrefolic is proven to be a real solution with beneficial innovated features that match totally to the requirements of physicians and doctors to provide effective solutions and increase consumers’ compliance.”
1. Cirillo M et al. “5-Methyltetrahydrofolate and vitamin B12 supplementation is associated with clinical pregnancy and live birth in women undergoing assisted reproductive technology.” International Journal of Environmental Research and Public Health, vol. 18, no 23 (2021): 12280, https://doi.org/10.3390/ijerph182312280