Slimaluma Strengthened by Animal Science

January 5, 2011

Results of a recent rat study indicate that the Indian plant extract Caralluma fimbriata (commercially known as Slimaluma) can significantly increase measures of appetite suppression.

Results of a recent rat study indicate that the Indian plant extract Caralluma fimbriata (commercially known as Slimaluma) can significantly increase measures of appetite suppression.

The study has been published in the Journal of Nutrition and Metabolism.

Rats were assigned to one of three groups: untreated control, control with a cafeteria diet or the cafeteria diet combined with CFE for 90 days. Within the treatment group, three different dosages of CFE (25, 50, and 100 mg/kg of bodyweight) were administered through gavage feeding.

In checking for changes to appetite markers, the researchers observed a significant and dose-dependent decrease in food intake, prevention of weight gain (as  body weight, liver weight, and fat pad mass), and even “dramatically higher” increases in serum leptin levels with CFE. Leptin is a hormone believed that has been linked to appetite suppression.

“This small scale study suggested that Caralluma fimbriata extract showed pronounced dose-dependent appetite suppressantand antiobesogenic effects on a sample of rats feda cafeteria diet,” wrote the study’s author. “These data, combined with existing CFEclinical trial findings, indicate that CFE has thepotential to curb obesity and the pathologies linked to obesity.”

Slimaluma, a CFE ingredient, is produced by Gencor Pacific (Anaheim, CA).