Results showed that in a cumulative responder analysis, subjects taking 500 mg of Rhuleave-K saw a 62% improvement, compared to placebo.
Photo © AdobeStock.com/estradaanton
A recent study1 published in IOSR Journal of Dental and Medical Sciences found that supplementation with a blend of Boswellia serrata and Curcuma longa called Rhuleave-K, from Arjuna Natural Pvt Ltd., helped relieve acute musculoskeletal pain from exercise. In the prospective, randomized, double-blind study, 40 healthy male and female subjects between the ages of 18 and 65 with acute musculoskeletal pain following exercise from the previous 24 hours, with a resting Numerical rating scale (NRS) of 5 or above on a 0-10 scale, were given either a single 500 mg dose of Rhuleave-K or placebo.
The primary outcome was the pain intensity difference at 6 hours based on the NRS and total pain relief based on the categorical pain relief scale (PRS) every 30 minutes up to 6 hours. Secondary outcomes were perceptible and meaningful pain relief as well as sensory and affective pain using McGill Pain Questionnaire-Short Form (MPQ-SF). Results showed that in a cumulative responder analysis, subjects taking the herbal blend saw a 62% improvement, compared to placebo. Subjects taking Rhuleave-K also saw significant improvements in total pain relief, perceived pain relief, quality of pain relief in sensory and affective domains, as well as MPQ-SF scores.
This present study saw significant effects at half the dose of prior trials on the blend which gave subjects 1000 mg doses. “There was a distinct gap in the herbal space for fast relief of acute pain,” said Benny Antony, PhD, joint managing director for Arjuna, in a press release. “Rhuleave-K is composed of all-natural botanicals, well-known in traditional Indian medicine and has seen growing support from the scientific community for their strong anti-inflammatory capacity. But more than anti-inflammatory, it’s the analgesic—or nociceptive—action which makes Rhuleave K stand out. And being able to halve the dose makes it extremely affordable, opening more options for creating new formulations using Rhuleave-K.”
The blend also includes black-sesame seed oil as an effective carrier agent for the Boswellia serrata and Curcuma longa extracts, as well as also contributing anti-inflammatory benefits. “These ingredients were not as successful individually for fast relief of pain,” explained Antony. “To our knowledge, Rhuleave-K —crafted through Arjuna’s proprietary Speedtech process—is the first such blend of botanicals clinically documented to offer fast pain relief in acute musculoskeletal pain and pain following exercise.”
Reference
Recent animal study finds that Lysoveta may help reduce neonatal brain injury
July 17th 2024A recent animal study found that lysophosphatidylcholine (LPC)-bound omega-3 long-chain polyunsaturated fatty acids (LCPUFAs), marketed as Lysoveta by Aker BioMarine, protected against neonatal hypoxic-ischemic (HI) brain injury in mice.
FDA and FTC issue more warning letters to copycat delta-8 THC food products
July 16th 2024The U.S. Food and Drug Administration and Federal Trade Commission have jointly issued warning letters to five companies for selling copycat food products containing delta-8 THC in violation of the Federal Food Drug and Cosmetic Act.