A new scientific review states that the naturally occurring form of p-synephrine exhibits at least twice the physiological activity as does the synthetic form.
A new scientific review states that the naturally occurring form of p-synephrine, an ingredient present in bitter orange extract, exhibits at least twice the physiological activity as does the synthetic form of p-synephrine.
The review by Sidney J. Stohs, PhD, called “Stereochemical and Physiological Differences Between Naturally Occurring p-Synephrine and Synthetic p-Synephrine,” states that synthetic p-synephrine enables only one-half of a synthetic p-synephrine formula to bind to receptors. By stimulating beta-3 receptors, p-synephrine can help to increase thermogenesis and lipolysis.
Stohs is Dean Emeritus at the School of Pharmacy and Health Professions at Creighton University Health Sciences Center.
The natural form of p-synephrine is present in Advantra Z, a patented bitter orange extract from Nutratech Inc. (West Caldwell, NJ). The ingredient is touted as an all-natural thermogenic ingredient for weight loss, fitness, and energy. Stohs’s review also points out that natural bitter orange extracts contain flavonoids and other protoalkaloids that synthetic versions do not.
The Nutritional Outlook Podcast Episode 33: Keeping up with contract manufacturing
July 26th 2024Nutritional Outlook talks to Lauren Samot, commercial innovation leader, and Blayney McEneaney, sales executive at Vitaquest International, about trends within the contract manufacturing space, and the ways in which contract manufacturers like Vitaquest keep up with the market and differentiate themselves from the competition.