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A study recently published in the Journal of Arthritis found that supplementation with NEM brand eggshell membrane (Stratum Nutrition; Carthage, MO) supports joint pain and stiffness in adults with knee osteoarthritis.
A study recently published in the Journal of Arthritis1 found that supplementation with NEM brand eggshell membrane (Stratum Nutrition; Carthage, MO) supports joint pain and stiffness in adults with knee osteoarthritis (OA). In the study, 70 subjects with knee OA were randomized to receive either 500 mg of eggshell membrane, once dairy, or placebo, for 60 days. The primary outcomes were pain and stiffness in subjects, determined with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Visual Analog Scale for Pain (VAS pain) and Lequesne Algofunctional Index measured after 10, 30 and 60 days of supplementation.
Results showed that supplementation with the eggshell membrane reduced overall WOMAC scores at 10 days by 16.6%, at 30 days by 31.8%, and 60 days by 46.7%, compared to baseline. WOMAC pain scores decreased significantly at day 10 by 19.8% and WOMAC stiffness scored decreased significantly at day 10 by 12.9%. VAS pain scored decreased by 19.6% at day 10, 31.8% at day 30, and 49% at day 60. Overall Lequesne Algofunctional Index scores decreased by 11.2% at day 10, 24% at day 30, and 36.8% at day 60. While subjects showed continued reductions in the primary outcomes throughout the course of the trial, statistical significance for each measure was only reached at day 10.
These measures confirm that supplementation with NEM brand eggshell membrane may help reduce pain and improve flexibility in joints. Because of these benefits, supplementation with the supplement may also reduce the use of analgesics.
1. Damjanov N et al. “NEM® Brand Eggshell Membrane in the Treatment of Pain and Stiffness Associated with Knee Osteoarthritis: An Open Label Clinical Study.” Journal of Arthritis, vol. 8, no. 5 (2019)