Probiotic strain from Blis Technologies Limited shows oral health benefits in recent studies

May 26, 2020

Two recent studies have found that a patented strain of Streptococcus salivarius, called Blis M18 from Blis Technologies Limited, inhibited the growth of bacteria that causes black teeth staining. 

Two recent studies have found that a patented strain of Streptococcus salivarius, called Blis M18 from Blis Technologies Limited, inhibited the growth of bacteria that causes black teeth staining. One of the studies, an in vitro study1, found that Blis M18 significantly decreased the pathogenic bacterial growth in a dose dependent manner, and has stronger antimicrobial activity compared to a Lactobacillus reuteri strain.

In the other, a randomized controlled study2, 58 children between the ages of 4 and 10 presenting with black stains in their teeth were given either Blis M18 or no treatment after undergoing professional removal of the stains. The subjects were assessed after three and six months. Results showed that the black stains returned after three months in 21.2% of children taking the probiotic, and in 50% of children receiving no treatment. After 6 months, black stains were detected in 32.1% of children taking the probiotic, and in 53.8% of the children receiving no treatment.

“BLIS Technologies continues to produce stellar clinical research that shows the many different benefits and mechanisms of action of BLIS M18. In this most recent clinical trial, we can see how the unique bacteriocins and enzymes produced by BLIS M18 not only help prevent the formation of dental plaque, but also help prevent the activity of specific bacteria responsible for black teeth stains,” said Alexis Collins, product manager at Stratum Nutrition, North American distributor of Blis Technologies’ ingredients, in a press release. “There are undoubtedly more actions of BLIS M18 that benefit dental and gum health, and we are proud to be partnered with BLIS Technologies as they continue to pursue research on this unique oral-colonizing probiotic.”

References:

1. Gobbi E et al. “In vitro inhibitory effect of two commercial probiotics on chromogenic
Actinomycetes.” European Archives of Paediatric Dentistry, Published online ahead of prints on February 7, 2020.

2. Bardellini E et al. “Does Streptococcus salivarius strain M18 assumption make black stains disappear in children?” Oral Health & Preventative Dentistry, vol. 18, no. 2 (2020): 161-164