Testosterone concentrations in men are known to decrease at a rate of 1%-2% per year after the age of 40. This decrease can be associated with a decrease in sexual activity and desire, as well as potential negative effects on musculoskeletal and metabolic health. Results from a recent 12-week double-blind, placebo-controlled study led by Amanda Rao from the University of Sydney (Sydney, Australia) indicate that fenugreek extracts may be a natural way to enhance testosterone levels and improve symptoms of androgen deficiency.
In the study, researchers assessed the effect of Testofen, a branded ingredient from Gencor (Irvine, CA). This extract of fenugreek containing steroidal saponins, and specifically furostanol glycosides, was given at a dose of 600 mg/day, or placebo, to the study subjects, which included 120 healthy men aged 43 to 75.4 Participants were assessed using the Aging Male Symptom (AMS) questionnaire, which measures psychological, somatic, and sexual parameters associated with androgen deficiency. Sexual function and drive were evaluated, as were serum total and free testosterone levels.
Fenugreek supplementation led to significant decreases in the AMS score compared to placebo. Sexual function also improved—specifically, the number of morning erections and frequency of sexual activity. Total and free testosterone levels showed statistically significant increases after 12 weeks in the fenugreek group, indicating its effectiveness in improving parameters associated with androgen deficiency.
4. Rao A et al., “Testofen, a specialized Trigonella foenum-graecum seed extract reduces age-related symptoms of androgen decrease, increases testosterone levels and improves sexual function in healthy aging males in a double-blind randomised clinical study,” Aging Male, vol. 19, no. 2 (June 2016):134-142
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